N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene)methanamine, commonly known as a Schiff base derivative, is an intermediate in the synthesis of the antidepressant sertraline hydrochloride. This compound plays a crucial role in the manufacturing process of sertraline, which is widely prescribed for depression and anxiety disorders.
N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene)methanamine, commonly known as a Schiff base derivative, is an intermediate in the synthesis of the antidepressant sertraline hydrochloride. This compound plays a crucial role in the manufacturing process of sertraline, which is widely prescribed for depression and anxiety disorders.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Serves as a key intermediate in the production of sertraline hydrochloride, an antidepressant medication.
Utilized in medicinal chemistry studies focused on developing and optimizing antidepressant compounds.
This Schiff base derivative serves as a crucial intermediate in the synthesis of sertraline hydrochloride, a widely used antidepressant. Its specific chemical structure enables the final product to interact effectively with serotonin receptors.
The Schiff base configuration ensures that sertraline exhibits the appropriate selective serotonin reuptake inhibition (SSRI) activity, making it effective in treating depression and anxiety.
Yes, this Schiff base intermediate is produced on a large scale by chemical manufacturers and is essential for producing sertraline at an industrial scale.
Apart from sertraline, this intermediate can be used to create other Schiff base derivatives that are useful in developing new antidepressants or other bioactive molecules.
As a pharmaceutical intermediate, it should be handled with care and appropriate protective equipment should be used. Always follow the safety guidelines provided by the manufacturer.
N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene)methanamine is primarily used in the production of sertraline, which is prescribed for depression and anxiety disorders.
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