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4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one (NPP-14) (Tetralone) (CAS NO:79560-19-3)

4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one, commonly known as Tetralone, is an intermediate in the synthesis of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders. Tetralone serves as a key building block in the pharmaceutical manufacturing process of Sertraline.​

4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one (NPP-14) (Tetralone)
4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one (NPP-14) (Tetralone)

4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one, commonly known as Tetralone, is an intermediate in the synthesis of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders. Tetralone serves as a key building block in the pharmaceutical manufacturing process of Sertraline.​

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Industries

Pharmaceutical

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Category

Pharmaceutical Actives & Precursors

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Sub-category

Intermediates & Precursors

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Chemical Properties & Specifications

Applications of 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one (NPP-14) (Tetralone)

Pharmaceutical Industry

Used as an intermediate in the synthesis of Sertraline.​

Research & Development

Serves in the development of other bioactive molecules and as a reference standard in analytical studies.

Have Questions About 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one (NPP-14) (Tetralone)?
We've Got Answers.

Tetralone is primarily used as an intermediate in the synthesis of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders.

Tetralone serves as a precursor in the synthesis of Sertraline, providing key functional groups that are essential for the final bioactive structure of the medication.

Yes, Tetralone should be handled with care. Personal protective equipment (PPE), including gloves, goggles, and lab coats, is recommended to prevent direct contact. Follow standard laboratory safety procedures when handling this intermediate.

Tetralone is commonly analyzed using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to monitor the synthesis process and ensure the purity of Sertraline.

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