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2-[1-(Mercaptomethyl)cyclopropyl]acetic acid (Montelukast) (CAS NO:162515-68-6)

1-(Mercaptomethyl)cyclopropaneacetic acid is a key intermediate in the synthesis of Montelukast, a leukotriene receptor antagonist used for the treatment of asthma and allergic rhinitis. This compound features a cyclopropane ring with a mercaptomethyl group, playing a crucial role in building the active pharmaceutical ingredient.​ Also known as 1-(MERCAPTOMETHYL) CYCLOPROPANE ACETIC ACID

2-[1-(Mercaptomethyl)cyclopropyl]acetic acid (Montelukast)
2-[1-(Mercaptomethyl)cyclopropyl]acetic acid (Montelukast)

1-(Mercaptomethyl)cyclopropaneacetic acid is a key intermediate in the synthesis of Montelukast, a leukotriene receptor antagonist used for the treatment of asthma and allergic rhinitis. This compound features a cyclopropane ring with a mercaptomethyl group, playing a crucial role in building the active pharmaceutical ingredient.​ Also known as 1-(MERCAPTOMETHYL) CYCLOPROPANE ACETIC ACID

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Pharmaceutical Actives & Precursors

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Intermediates & Precursors

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Chemical Properties & Specifications

Applications of 2-[1-(Mercaptomethyl)cyclopropyl]acetic acid (Montelukast)

Pharmaceutical Manufacturing

Serves as a crucial intermediate in the synthesis of Montelukast, aiding in the production of medications for asthma and allergic rhinitis.

Agricultural Chemistry

It is utilized in the synthesis of certain pesticides and fungicides, contributing to crop protection by targeting specific plant pathogens.​

Biochemical Research

Researchers employ this compound to study cyclopropyl-containing molecules, aiding in the development of new therapeutic agents with unique mechanisms of action.

Have Questions About 2-[1-(Mercaptomethyl)cyclopropyl]acetic acid (Montelukast)?
We've Got Answers.

This compound is a key intermediate in the synthesis of Montelukast, a medication used to treat asthma and allergic rhinitis.

It provides the structural foundation for Montelukast, contributing to the cyclopropane moiety essential in the API's mechanism of action.

Its stable properties and controlled reactivity make it an ideal intermediate for Montelukast synthesis, ensuring high yield and purity.

The highest demand is observed in North America, Europe, and Asia, where Montelukast is widely used for asthma management.

This intermediate is regulated under pharmaceutical import/export guidelines, requiring compliance with GMP and ISO standards in key markets.

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