1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)-ethanone, commonly referred to as DFTA, is an intermediate in the synthesis of Fluconazole and other azole-based antifungal medications. It is used in pharmaceutical manufacturing and research & development as part of the chemical pathway to producing COX-2 inhibitors and related therapeutic agents.
1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)-ethanone, commonly referred to as DFTA, is an intermediate in the synthesis of Fluconazole and other azole-based antifungal medications. It is used in pharmaceutical manufacturing and research & development as part of the chemical pathway to producing COX-2 inhibitors and related therapeutic agents.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Used as an intermediate in the synthesis of Fluconazole and related compounds.
Employed in the development of triazole-based antifungal agents and other bioactive molecules.
DFTA is an intermediate used in the synthesis of Fluconazole and other azole-based antifungal medications. It is an essential compound in the production of COX-2 inhibitors and other therapeutic agents.
It acts as a precursor in the synthesis of Fluconazole, providing a triazole ring system that is integral to the bioactive structure of the drug, a potent antifungal agent.
Yes, it should be handled with care. Use appropriate PPE (personal protective equipment) including gloves, goggles, and lab coats to avoid skin and eye contact. Follow standard laboratory safety protocols when working with this compound.
High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) are commonly used for detecting and quantifying DFTA in pharmaceutical formulations and ensuring the purity of Fluconazole.
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