Scimplify
Hero BGRounded Top
Rounded Bottom

Itraconazole ITC (CAS NO:84625-61-6)

Itraconazole is a triazole-class antifungal agent used to treat a variety of fungal infections by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. It is effective against a broad spectrum of fungi, including Aspergillus, Blastomyces, Histoplasma, and Candida species. Itraconazole is also a member of the triazoles class, dioxolane, N-arylpiperazine, dichlorobenzene, cyclic ketal, and aromatic ether. Derived from cis-ketoconazole, its imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group, and the acetyl group on the piperazine moiety is substituted by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. ECHA deprecated cas number is 84604-65-9.

Itraconazole ITC
Itraconazole ITC

Itraconazole is a triazole-class antifungal agent used to treat a variety of fungal infections by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. It is effective against a broad spectrum of fungi, including Aspergillus, Blastomyces, Histoplasma, and Candida species. Itraconazole is also a member of the triazoles class, dioxolane, N-arylpiperazine, dichlorobenzene, cyclic ketal, and aromatic ether. Derived from cis-ketoconazole, its imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group, and the acetyl group on the piperazine moiety is substituted by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. ECHA deprecated cas number is 84604-65-9.

industries-sectionindustries

Industries

Pharmaceutical

category-sectioncategory

Category

Pharmaceutical Actives & Precursors

sub-category-sectionsub-category

Sub-category

Active Pharmaceutical Ingredients (APIs)

Fast Response

Get a Quote

Details add in quote!

Minimum Order Quantity

Included in Quote

Lead Time

Included in Quote

Regional Availability

Included in Quote

Incoterms

Included in Quote

Intersect
Rounded Top

Chemical Properties & Specifications

Applications of Itraconazole ITC

Medical Treatment

Used to treat systemic and superficial fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis.

Dermatology

Effective in treating dermatophytoses and other cutaneous fungal infections

High Protein Binding therapeutics

Ensures prolonged circulation time and sustained therapeutic levels.

Oral and Topical Administration

Available in multiple formulations to suit different treatment needs.

Fungal infection treatments

Aspergillosis, blastomycosis, histoplasmosis Oral treatments for systemic fungal infections Cosmetic formulations aimed at improving hair growth (in some formulations)

Topical treatments

Onychomycosis

Oral treatments

Systemic fungal infections

Cosmetic formulations

Aimed at improving hair growth (in some formulations)

Have Questions About Itraconazole ITC ?
We've Got Answers.

Itraconazole is an antifungal medication used to treat a variety of fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis. It is also effective for fungal infections of the skin, nails, and internal organs.

Itraconazole is available in capsules, oral solutions, and intravenous forms. The capsules should be taken with a full meal to enhance absorption, while the oral solution is better absorbed on an empty stomach. Always follow your healthcare provider's instructions regarding dosage and administration.

Common side effects include nausea, diarrhea, abdominal pain, rash, and headache. If you experience severe side effects such as liver problems (yellowing of skin or eyes), heart failure symptoms, or severe allergic reactions, seek medical attention promptly.

Yes, certain medications may interact with Itraconazole, leading to serious side effects. Medications like cisapride, pimozide, quinidine, and certain statins (e.g., lovastatin, simvastatin) should not be taken with Itraconazole. Always inform your healthcare provider of all medications and supplements you are using.

The safety of Itraconazole during pregnancy or breastfeeding is not well-established. It is essential to consult your healthcare provider to weigh the potential risks and benefits before using this medication in such situations.

Itraconazole should be stored at room temperature, away from moisture and heat. Keep the medication in its original container, tightly closed, and out of reach of children.

itraconazole, 84625-61-6, Oriconazole, Sporanox, Itrizole, Itrizole (TN), 873066-43-4, Sporanox (TN), ITCZ, Itraconazol, Fungitraxx, Itraconazolo, Itraconazolum, Sporonox, Cladosal 100, 2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one, DTXSID3023180, Itraconazole (Sporanox), NSC-759239, Itraconazol [Spanish], Itraconazolum [Latin]

Itraconazole is manufactured globally, with key suppliers and manufacturers located in India, China, and several European countries. These regions are recognized for their large-scale pharmaceutical production capabilities and high-quality manufacturing standards. Leading suppliers in these regions adhere to (GMP), ensuring the consistent quality and regulatory compliance.

The assay specification for Itraconazole typically falls within the range of 98-102%, ensuring its potency and purity for pharmaceutical applications.

High-performance liquid chromatography (HPLC) is commonly used to test the purity and assay of Itraconazole, in line with pharmaceutical standards.

The minimum order quantity (MOQ) for Itraconazole may vary depending on the supplier, but it typically starts from 1 kg for bulk purchases.

Yes, pricing for Itraconazole can be customized based on order volume, frequency, and customer requirements, especially for long-term contracts or bulk orders.

Yes, formulation support is typically available for Itraconazole, particularly for topical formulations, oral solutions, and injectable forms.

Itraconazole is typically cGMP certified, and manufacturers may also hold certifications like USP, EP, and ISO for quality assurance and regulatory compliance.

Yes, documentation such as Certificates of Analysis (COA), GMP compliance certificates, and MSDS are available to confirm the product’s quality and regulatory compliance.

Yes, Itraconazole is available in both base and salt forms, depending on the intended formulation and application.

The preferred grade for Itraconazole export is typically USP grade or EP grade, which ensures compliance with international regulatory standards.

Yes, long-term supply contracts for Itraconazole can be arranged, particularly for pharmaceutical manufacturers, ensuring a steady supply for ongoing production needs.

India, North America, EU preferrably

Our Top Specialty Chemical Products

Antimony Trioxide
Top Right Icon

Antimony Trioxide

CAS No. : 1309-64-4

Category : Inorganic compound

Sub-Category : Flame retardants

Description: Antimony trioxide (Sb2O3) is an inorganic compound commonly used as a flame retardant and as a catal...

View Product
Kephalis - Sciclohexanone
Top Right Icon

Kephalis - Sciclohexanone

CAS No. : 36306-87-3

Category : Fragrance Ingredients

Sub-Category : Aroma Chemicals

Description: Kephalis is widley used in many industries. It plays a key role in the production of resins, coating...

View Product
Thioanisole
Top Right Icon

Thioanisole

CAS No. : 100-68-5

Category : Pharmaceutical Actives & Precursors

Sub-Category : Intermediates & Precursors

Description: Thioanisole is a colorless to light yellow liquid with an aromatic odor. It serves as a valuable int...

View Product
Magnesium Oxide
Top Right Icon

Magnesium Oxide

CAS No. : 1309-48-4

Category : Inorganic compound

Sub-Category : Magnesium compounds

Description: Magnesium oxide, commonly known as magnesia, is a white hygroscopic solid mineral that occurs natura...

View Product
Benzyl Chloride
Top Right Icon

Benzyl Chloride

CAS No. : 100-44-7

Category : Organic Intermediate

Sub-Category : Reagents

Description: Benzyl Chloride is a colorless to pale yellow liquid with a pungent odor. It is primarily used as an...

View Product
Fast Response

Get a Quote

Fast Response

Get a Quote