Fexofenadine Hydrochloride is a second-generation, non-sedating antihistamine that selectively inhibits peripheral H1-receptors. It is primarily used to alleviate symptoms associated with allergic rhinitis, urticaria, and seasonal allergies, without causing drowsiness due to minimal central nervous system penetration.
Fexofenadine Hydrochloride is a second-generation, non-sedating antihistamine that selectively inhibits peripheral H1-receptors. It is primarily used to alleviate symptoms associated with allergic rhinitis, urticaria, and seasonal allergies, without causing drowsiness due to minimal central nervous system penetration.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Antihistamines, Second-generation H1 receptor antagonist
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Chemical Properties & Specifications
Used in the treatment of seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives).
Can be used as a symptom reliever for allergic reactions caused by pollen, dust mites, animal dander, and insect stings.
Available in over-the-counter formulations for allergy relief.
Fexofenadine Hydrochloride is an antihistamine used to relieve allergy symptoms such as runny nose, sneezing, itchy or watery eyes, and itching of the throat or nose. It's effective in treating conditions like seasonal allergic rhinitis and chronic idiopathic urticaria.
It's recommended to take Fexofenadine Hydrochloride on an empty stomach with water. Avoid consuming it with fruit juices like grapefruit, orange, or apple, as they can decrease the drug's absorption and effectiveness.
Common side effects may include headache, dizziness, nausea, and drowsiness. If you experience severe allergic reactions or symptoms like difficulty breathing, seek medical attention promptly.
Fexofenadine can interact with certain medications, including antacids containing aluminum or magnesium. It's essential to consult your healthcare provider before combining it with other drugs.
If you're pregnant or planning to become pregnant, discuss with your doctor whether Fexofenadine is safe to take.
When sourcing Fexofenadine Hydrochloride API, it's essential to ensure that the manufacturer complies with international quality standards such as WHO-GMP and FDA regulations.
keyparameter is Control of Impurities,Polymorphic Form Control,Particle Size Distribution,Residual Solvent Levels.
During wet granulation, Fexofenadine Hydrochloride can undergo phase transformations, potentially affecting its bioavailability and stability. To mitigate, focus-Optimize Water Content, Monitor Granulation Parameters, Implement In-Process Controls.
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