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DTT (DL-1,4,Dithiothrotol) (CAS NO:3483-12-3)

"DTT (DL-1,4-Dithiothreitol) is a small-molecule reducing agent widely used in biochemistry and molecular biology. It functions by reducing disulfide bonds in proteins and peptides, helping maintain enzyme activity and protein stability by preventing oxidation. It is an enantiomer of a L-1,4-dithiothreitol. A reagent commonly used in biochemical studies for reducing disulphides to dithiols."

DTT (DL-1,4,Dithiothrotol)
DTT (DL-1,4,Dithiothrotol)

"DTT (DL-1,4-Dithiothreitol) is a small-molecule reducing agent widely used in biochemistry and molecular biology. It functions by reducing disulfide bonds in proteins and peptides, helping maintain enzyme activity and protein stability by preventing oxidation. It is an enantiomer of a L-1,4-dithiothreitol. A reagent commonly used in biochemical studies for reducing disulphides to dithiols."

Industries

Pharmaceutical

Category

Pharmaceutical Actives & Precursors

Sub-category

Intermediates & Precursors

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Chemical Properties & Specifications

Applications of DTT (DL-1,4,Dithiothrotol)

Biochemistry and Molecular Biology

Used as a reducing agent to maintain protein stability.

Protein Folding Studies

Prevents incorrect disulfide bond formation in proteins, aiding in protein folding studies.

Enzyme Stability Enhancement

Protects enzymatic activity by maintaining thiol groups in their reduced state.

RNA and DNA Research

Used in electrophoresis to prevent nucleic acid oxidation.

Have Questions About DTT (DL-1,4,Dithiothrotol)?
We've Got Answers.

DTT is widely used in biochemistry to reduce disulfide bonds in proteins and peptides, ensuring correct protein folding.

DTT functions as a reducing agent by donating electrons to disulfide bonds, preventing unwanted oxidation.

DTT is primarily used in pharmaceutical, biotechnology, and molecular biology industries for research and drug development.

DTT should be handled in a fume hood with protective gloves and eyewear due to its irritant properties.

Yes, DTT meets international safety standards including REACH, ISO 9001, and GMP compliance.

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